MA Li-feng1, CHEN Shao-rui2, SHEN Feng-juan2, LI Li-juan1, HUANG Wen-jie1, MA Ji-hai2
1. Hebei Chemical and Pharmaceutical Vocational Technical College, Shijiazhuang 050026, China; 2. College of Science, Hebei University of Science and Technology, Shijiazhuang 050018, China
Muscone which is the most important ingredient of natural musk,can be used as super fragrant and in medicine.Beause the nature source of muscone is limited,it is synthesized antifically. Three main synthesis methods of muscone were reviewed in recent years which were cyclization of open-chain difunctional group compounds, enlarging ring of large cyclic compound and inserting methyl. It was pointed out that the antifical synthesis methods of muscone had some disadvertages which were long synthesis routes， difficult operation, high production, low yield etc.,so they hardly achieve industrialization,and the inserting methyl method has been a research focus in recent years.
马丽锋，陈韶蕊，申凤娟，李丽娟，黄文杰，马吉海. 麝香酮的合成进展[J]. 煤炭与化工, 2014, 37(6): 31-34，87.
MA Li-feng, CHEN Shao-rui, SHEN Feng-juan, LI Li-juan, HUANG Wen-jie, MA Ji-hai. Process on Synthesis of Muscone. CCI, 2014, 37(6): 31-34，87.
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