In view of the wellbore failure in the inclined shaft of Xinsan Mine, the FLAC3D software was adopted to numerically simulate the deformation of the surrounding rock at the specific position of the inclined shaft under three conditions: unsupported, long anchor and joist steel. The support effect under three kinds of numerical simulations was summarized. The deformation law of surrounding rock in the weak inclined rock layer was obtained, and the final support scheme was determined by combining engineering examples. The results showed that the anchor support scheme had the best support effect at 700 m in numerical simulation, and the joist steel and anchor were used alternately in the support, with the best support effect.