Application of mid-infrared spectroscopy in cultivating innovative and entrepreneurial abilities of pharmaceutical college students - taking glucose as an example
Sang Yuqi1,2,3, Ji Yifan1, Li Shuangfan1, Zhang Zishuo1, Chen Chengrong1,#br#
Lv Qingfeng1, Kong Xiaomei1, An Haifei5
1.Shijiazhuang University College of Chemical Technology, Shijiazhuang 050035, China; 2. Shijiazhuang Key Laboratory of Medicinal Polymer Materials, Shijiazhuang 050035, China; 3. Anesthetic Technology Innovation Center of Hebei Province, Shijiazhuang 050035, China; 4. Hebei University of Science and Technology School of Chemical and Pharmaceutical Engineering, Shijiazhuang 050018, China; 5. Shijiazhuang University, Carbon Neutrality Research Center, Shijiazhuang 050035, China
The molecular structure of glucose was explored. The diffuse reflectance Mid-Infrared (MIR) spectroscopy experiments were conducted. The infrared absorption modes of the main functional groups of glucose include free O-H functional group stretching vibration mode (ν■), dimeric O-H functional group stretching vibration mode (ν■), polymer O-H functional group stretching vibration mode (ν■), CH2 functional group asymmetric stretching vibration mode (ν■), C-H functional group stretching vibration mode (νC-H), CH2 functional group symmetric stretching vibration mode (ν■), water molecule O-H functional group bending vibration mode (δ■), coupled with of CH2 functional group bending vibration and several bending vibration of functional groups such as OCH, CCH, COH etc (δ■ + δ■ + δ■ +δ■), C-O functional groups in COH structure stretching vibration mode (ν■), C-O functional group on sugar ring structure stretching vibration mode (ν■), OCH functional group bending vibration (δOCH), C-O-H functional group bending vibration (δC-O-H), sugar ring structure asymmetric stretching vibration mode (ν■), C-C-H functional group and O-C-H functional group bending vibration (δC-C-H + δO-C-H), O-C-H functional group with α-terminal isomerism structure bending vibration (δO-C-H-α-terminal isomerism structure), sugar ring structure symmetric stretching vibration mode (ν■), functional group vibration mode caused by νC-C and νC-O. Diffuse reflectance MIR spectroscopy can rapidly investigate the molecular structure of glucose
桑雨琪1,2,3，吉一帆1，李泷帆1，张子硕1，陈成荣1，吕庆丰1，孔晓美4，安海飞5. 中红外光谱法在药剂学的应用——以葡萄糖为例[J]. 煤炭与化工, 2026, 49(1): 151-160.
Sang Yuqi1,2,3, Ji Yifan1, Li Shuangfan1, Zhang Zishuo1, Chen Chengrong1,. Application of mid-infrared spectroscopy in cultivating innovative and entrepreneurial abilities of pharmaceutical college students - taking glucose as an example. CCI, 2026, 49(1): 151-160.
