Study on determination of R-3-Amino-1-butanol by gas chromatography
Liu Lirong1, Wang Xiaoru2,3, Mu Yumin1, Zhang Haoyue1, Yang Mengxi1, Liu Dong1, Ren Limei2,3
1. Mei bang mei he Biological Technology Corporation Ltd., Shijiazhuang 050000, China； 2. School of Chemical Engineering, Shijiazhuang University, Shijiazhuang 050035, China; 3. Hebei Provincial University Microbiology Pharmaceutical Application Technology Research and Development Center, Shijiazhuang 050035, China
Abstract：The content of R-3-aminobutanol was determined by gas chromatography internal standard method. The separation degree of R-3-aminobutanol and related solvents was relatively high.By comparing the external standard method with the internal standard method, the RSD values of the internal standard method(0.46% and 0.94%) are much smaller than that of the external standard method (2.75% and 2.17%). The linear relationship between the concentration of R-3-aminobutanol and the response ratio was good in the range of 5.0～99.0 mg/mL, he linear regression equation was Y=0.102 6X-0.199 3, R2=0.999 2, the limits of detection and quantitation of the method were 0.50 mg/mL and 1.52 mg/mL, respectively, the recovery rate was 95.2% ~ 99.7% and RSD was 0.13% ~ 0.97%. The experimental results show that the internal standard method of gas chromatography has high accuracy and good repeatability, and has wide application and reference value in the field of monitoring and quality control of finished products in the production process
刘丽荣1，王晓茹2,3，穆玉敏1，张浩月1，杨梦茜1，刘 东1，任丽梅2,3. 气相色谱法检测R-3-氨基丁醇的研究[J]. 煤炭与化工, 2023, 46(6): 148-152，160..
Liu Lirong1, Wang Xiaoru2,3, Mu Yumin1, Zhang Haoyue1, Yang Mengxi1, Liu Dong1, Ren Limei2,3. Study on determination of R-3-Amino-1-butanol by gas chromatography. CCI, 2023, 46(6): 148-152，160..
