Fault is one of the main factors of mine roof accident and water outburst disaster, which seriously affects the safe and efficient production of coal mine. In order to solve the problem of fault water disaster, taking No.316 mining area of Xin 'an Coal Industry Co., Ltd. ( referred to as Xin 'an Coal Mine ) of Zaozhuang Mining Group as the engineering background, theoretical analysis, numerical simulation and other methods were used to study the concentrated track roadway and concentrated belt roadway passing through F1 fault in No.316 mining area by means of transient electromagnetic method, in-seam seismic exploration, grouting reinforcement and coring verification. The results showed that the roof and floor strata in front of the centralized track roadway and the centralized belt roadway in No.316 mining area were relatively weak in water abundance, and it was found that the F1 fault did not contain (conduct) water through drilling exploration. The existence of F1 fault had a great influence on the stability of surrounding rock in roadway excavation, which could lead to obvious roof subsidence and floor heave, and the failure depth of surrounding rock in roadway was obviously larger than that in normal stratum. Through grouting reinforcement, the geological property modification of F1 fault was realized, and the problem of roadway excavation conducting fourteen limestone and Ordovician limestone aquifers was solved.