This paper analyzed and studied the geological and hydrogeological conditions of Jingu Coal Industry Co., Ltd. in Guxian County, Shanxi Province, and found out the main water filling factors of the mine, including atmospheric precipitation and surface water, aquifer water, goaf water and so on. Through field measurement and data analysis, the hydrological characteristics of each aquifer and its relationship with mine water filling were determined, and the height of caving zone and water flowing fractured zone and the water outburst coefficient of Ordovician limestone water were calculated. On this basis, the area comparison method was used to predict the mine water inflow, and the normal mine water inflow was 54.58 m3 / h, and the maximum water inflow was 81.87 m3 / h. This study provided a scientific basis for the prevention and control of mine water disasters in Jingu Coal Industry, which was helpful to improve the safety production level of the mine. It had important reference value for the evaluation of coal mine water filling factors and the prediction of water inflow under similar geological conditions.