In order to reduce the power consumption of main fan and improve economic efficiency, two methods of equalization state adjustment and non-equilibrium state adjustment were proposed, and emphasis was placed on conditional mines. Equilibrium adjustment should be used as much as possible in terms of management and efficiency. For the adjustment under non-equilibrium state, according to the three basic laws of ventilation, the reasonable working range of the actual wind pressure curve of the fan was fitted to the approximate equation, and an analytical method was proposed. The method was applied to the case for analysis and research, which was practical and feasible.