The grouting effect of the main system of 北二一transportation roadway in Huangling Mine was analyzed by statistical analysis，with geophysical prospecting and drilling peephole technology. The results showed that the grouting method exerted an important role in roadway maintenance. Acoustic detection and geophysical prospecting. were simultaneously used to analyze and evaluate the grouting effect， which laid the foundation for further optimizing the grouting parameters， improving the reinforcement effect of the roadway and ensuring the service life of the roadway.