In karst development area, mine safety production was also threatened by conducting water collapse column. Water disaster accidents caused by passive revealing could be avoided through reasonable means. For example, concealed water collapse column could be discovered on the basis of using available hydrological information to active prevention of karst collapse column in the mine and changing from passive mining exploration to active exploration. Taking a few conducting water collapse columns of Fangezhuang Mine discovered in advance as examples, relative experience and methods were summarized, which provided reference to similar mine active prevention of concealed water karst collapse column.