The positioning of the target layer for slurry reinforcement is one of the key issues to be considered when formulating the surface area treatment plan. It is not only necessary to make the thickness of the water barrier meet the requirements of the sudden water coefficient, but also to select the layer section with relatively developed karst fissures and strong injectability so that the slurry can be fully diffused during the injection. Geophysical logging methods are often used for lithological stratification of borehole profiles, determination of aquifers, karst development zones and hydrogeological parameters, etc. The use of multiple logging techniques for comparative analysis, together with borehole coring and hydrological observation data, can provide a basis for accurate positioning of the target layer for regional management on the ground.