In order to solve the threat of limestone ash water damage in Yangdong Mine, it is necessary to adopt regional advance management and water control technology, to explore the coal seam floor aquifer and the ash aquifer perpendicular guide water-bearing structure, and injection reinforcement. 8470 working face of Yangdong Mine of Fengfeng Group was taken as an example, water burst coefficient method was adopted to evaluate and analyze floor water, the danger of floor water was determined, the purpose layer of regional governance was studied and determined, structural position was analyzed, with reasonably arranging regional governance borehole, locating the red line of regional governance, the technology provided data support for the maximum upper limit of governance, ensured the theoretical and scientific nature of regional governance technology, and safe minin.