In view of the problem of large deformation of surrounding rock in the dedicated air return roadway in the mid-level of the 320 m mining level in Duanshi l Mine, pre-stressed anchor based on working conditions and grouting support were combined, the support parameters were calculated, with investigation of the effect. The results showed that there were a few ledges and bottom drums in the test roadway. It was necessary to ensure the construction quality of the bolts in the two sides of rock mass with remarkable protective effect.