Excavation-anchor integrated machine is the future development trend of coal mine equipment. In this paper, the sliding frame in the cutting device of JM340 excavation-anchor integrated machine in Baoxin Coal Industry is taken as the research object. Based on topology optimization technology and HYPERWORKS finite element software, the sliding frame is optimized and improved. The results of topology optimization show that the topological values of the sliding frame are very different, which indicates that the stress in different regions shows the characteristics of inhomogeneity. The structure optimization is carried out by setting reinforcing ribs on both sides of the vertical plate, setting reinforcing ribs in the box area of the cutting oil cylinder connection seat, and removing the material in the middle area of the guide sleeve connection box. The weight of the optimized sliding frame is reduced by 3%. After about one year of practical application, it is found that the sliding frame has good operation stability and can improve its service life.