Study on diffuse reflectance mid infrared spectroscopy of isoflurane molecular structure
Wang Yun1, Sang Yuqi2,3,4, Yang Tianfeng1, Zhao Xiaoyu1, Zhang Zishuo2, Shen Bo2, Peng Shuaining5,6
1. Hebei Institute for Drug and Medical Device Control, Shijiazhuang 050000, China; 2. Shijiazhuang University College of Chemical Technology, Shijiazhuang 050035, China; 3. Shijiazhuang Key Laboratory of Medicinal Polymer Materials, Shijiazhuang 050035, China; 4. Anesthetic Technology Innovation Center of Hebei Province, Shijiazhuang 050035, China;
5. Department of Pharmacy, Hebei General Hospital, Shijiazhuang 050051, China; 6. Hebei Key Laboratory of Clinical Pharmacy, Shijiazhuang 050051, China
The molecular structure of isoflurane was explored. The diffuse reflectance mid infrared (MIR) spectroscopy experiments on the molecular structure of isoflurane was conducted. The results showed that the infrared absorption modes of the molecular structure of isoflurane mainly include: CF3 functional group asymmetric stretching vibration mode (ν■), CF3 functional group symmetric stretching vibration mode (ν■), CF2 functional group asymmetric stretching vibration mode (ν■), CF2 functional group symmetric stretching vibration mode (ν■), C-O functional group stretching vibration mode (ν■) and C-Cl functional group stretching vibration mode (ν■). Spectrum software interpolation peak algorithm, spectrum software center algorithm and origin software algorithm, among which using brigin softuare algorithm, diffuse reflectance MIR spectroscopy can provide richer spectral information.
