In view of the problems of local regional high water level, high water temperature and large water volume anomalies and hidden dangers of water inrush in Wutongzhuang Mine during the advanced drilling period of the underground construction of the -470 level north wing track roadway, the drilling construction was carried out to the underlying limestone layer of the coal seam floor, and the overall technical route of water prevention and control combining the underground drilling exploration and treatment project with the ground regional treatment project was proposed. Through the construction borehole inclinometer and drainage experiment, combined with the comprehensive analysis of the borehole data above and below the well, the hydrogeological conditions in front of the excavation were identified, the types of water disasters were analyzed and judged, and the hydrological anomaly area was excluded. The exploration found a hidden fault with H = 21 m developed in the Daqing limestone layer, and it was judged that the fault did not conduct ( contain ) water, and there was no need to set up waterproof coal pillars. Through underground drilling and regional control drilling grouting, the fractures of each aquifer were blocked, the water abundance of the aquifer was weakened, and the water isolation capacity of the floor was enhanced. This technology provided a reference for the prevention and control of water in similar mine working faces.