Aiming at the problems such as floor heave, roof breakage and large deformation of surrounding rock in the 13111 soft rock drainage roadway of Baiping Mine, the deformation characteristics of surrounding rock of roadway were analyzed by means of water test and electron microscope scanning. It was concluded that there was a large amount of Yimeng mixed layer in the mudstone layer of roadway floor and upper side, and the rock layer was prone to expansion and argillation when exposed to water, resulting in the failure and deformation of surrounding rock of roadway. Based on this, a numerical model was established, three support schemes were given and numerical simulation analysis was carried out. It was concluded that the support method of "anchor net + shotcrete + anchor cable + anchor injection" had the best effect on controlling the deformation of roadway surrounding rock. The application results showed that after the newly designed support scheme was adopted, the maximum displacement of two sides of the roadway was 95mm, and the maximum displacement of top and bottom was 118mm. The deformation of roadway surrounding rock could be effectively controlled, and the expected effect was achieved.