Abstract：To investigate the stability of elemene emulsion injection after clinical compatibility and guide clinical medication. The changes of appearance, pH value, particle size distribution, elemene content and related substances of elemene emulsion injection after compatibility with three diluents (0.9% sodium chloride injection, 5% glucose injection and 20% fat emulsion injection) within 0 ~ 30.0 h were investigated by using pH meter, particle size distribution meter and gas chromatograph. Elemene emulsion injection showed no significant change in appearance over time in three diluents; The fluctuation of pH value, 90% particle size, 100% particle size, and average particle size over time is relatively small; Content: The amount of β、δ＋γ elemene is relatively stable and does not fluctuate significantly over time; Related substances, the sum of 0.96 peak+ β-butylene, total impurities, and maximum impurities are relatively stable, with little fluctuation over time. Within 0 ~ 30.0 hours, the stability of elemene emulsion injection in 0.9% sodium chloride injection, 5% glucose injection, and 20% fat emulsion injection is good, which can ensure medication safety.
梅冬雪，杨友剑，刘小丹，王一惠，徐文书. 榄香烯乳状注射液临床配伍稳定性研究[J]. 煤炭与化工, 2023, 46(5): 138-142.
Mei Dongxue, Yang Youjian, Liu Xiaodan, Wang Yihui, Xu Wenshu. Study on the stability of clinical compatibility of elemene emulsion injection. CCI, 2023, 46(5): 138-142.
[ 1 ] 杨家庭，丁成芳，刘连杰，等. 臭氧脱硝技术在稀贵多金属烟气治理中的应用[ J ]. 铜业工程， 2022（ 1 ）：45 - 48.
[ 2 ] 杨晓武，朱智颖，汤 洛. 臭氧脱硝工艺在冶炼环集烟气治理中的应用[ J ]. 硫酸工业，2020（ 5 ）：13 - 16.
[ 3 ] 罗香銮，刘全辉，邹 新. 生物质锅炉臭氧脱硝技术的应用[ J ]. 环境与发展，2019（ 3 ）：80 - 81.
[ 4 ] 孙军如. 烧结烟气臭氧脱硝工艺设计[ J ]. 现代冶金，2017，
45（ 2 ）：18 - 20.
[ 5 ] 马 强. 烟气中多种污染物超低排放的活性分子氧化及一体化脱除机理研究[ D ]. 杭州：浙江大学，2016.
[ 6 ] 林法伟. 活性分子臭氧耦合催化深度脱除烟气中氮氧化物的基础特性研究[ D ]. 杭州：浙江大学，2018.
[ 7 ] 张逸伟，唐海荣，何 勇，等. 臭氧低温氧化烟气脱硝过程中的氮平衡试验研究[ J ]. 化工学报，2022，73（ 4 ）：1 732
- 1 742.
[ 8 ] 黄元凯. 湿法脱硫脱硝过程中硝酸盐气溶胶的生成机理与控制[ D ]. 杭州：浙江大学，2021.
[ 9 ] Sun CL, Zhao N, Zhuang ZK, etal. Mechanisms and reaction pat-
hways for simultaneous oxidation of NOX and SO2 by ozone determined by in situ IR measurements[ J ]. J. Hazard. Mater. 2014，274: 376 - 383.
[ 10 ] Zhang J, Zhang R, Chen X, et al. Simultaneous removal of NO and SO2 from flue gas by ozone oxidation and NaOH absorption[ J ]. Industrial and Engineering Chemistry Research, 2014, 53: 6 450 - 6 456.
[ 11 ] Dora J, Gostomczyk M, Jakubiak M, et al. Parametric studies of the effectiveness of NO oxidation process by ozone[ J ]. Chemical and Process Engineering, 2012, ( 32 ): 229 - 239.
[ 12 ] 马希红，王建国，朱 蒙，等. 低温氧化脱硝技术脱除烟气NOX试验研究[ J ]. 能源与环境，2022（ 3 ）：72 - 74.
[ 13 ] Wang Z H, Zhou J H, Zhu Y Q, et al. Simultaneous removal of NOx, SO2 and Hg in nitrogen flow in a narrow reactor by ozone injection: experimental results[ J ]. Fuel Processing Technology, 2007, 88( 8 ): 817 - 823.
[ 14 ] Lin F W, Wang Z H, Ma Q, et al. N2O5 formation mechanism dur-
ing the ozone-based low-temperature oxidation deNOx process[ J ]. Energy & Fuels, 2016, 30( 6 ): 5 101 - 5 107.
[ 15 ] Wang H Q, Zhou K, Sun C L, et al. Numerical evaluation of the ef-
fectiveness of NO2 and N2O5 generation during the NO ozonation process[ J ]. Journal of Environmental Sciences, 2016, 41( 3 ): 51 - 58.
[ 16 ] 邹 洋，刘霄龙，朱廷钰，等. 臭氧氧化结合钙法同时脱硫脱硝的研究[ J ]. 河北冶金，2019， 增刊（ 1 ）：22 - 26.
[ 17 ] Ji R, Wang J, Xu W, et al. Study on the key factors of no oxidation using o3: The oxidation product composition and oxidation selectivity[ J ]. Industrial & Engineering Chemistry research, 2018, 57( 43 ): 14 440 - 14 447.
[ 18 ] Dora J, Gostomczyk M, Jakubiak M, et al. Parametric studies of the effectiveness of NO oxidation process by ozone[ J ]. Chemical and Process Engineering, 2009, 30: 621 - 634.
[ 19 ] Jakubiak M, Kordylewski W. The effect of ozone feeding mode on the effectiveness of NO oxidation[ J ]. Chemical and Process Engineering, 2011, 32: 229 - 239.
