Abstract: Water damage prevention and control in goaf is one of the key points of mine water damage prevention and control. In the mining area with multiple coal seams mining, the goaf water is formed after the upper coal seam is mined. When the close coal seam is mined, it is easy to threaten the lower coal seam mining. In order to eliminate the hidden danger of water accumulation caused by conduction between water conduction fracture zone and overlying No.2-2 coal seam working face goaf during the mining of No.30205 face in Nanliang Mine, two geophysical exploration methods, audio electrical perspective and mine transient electromagnetic method, were used to explore the water abundance distribution in overlying goaf of No.30205 face. In the later stage, the drilling holes were arranged according to the geophysical exploration results to verify the accuracy of geophysical exploration results, and the accumulated water in the goaf of overlying coal seam was discharged. The practice showed that the mine comprehensive geophysical exploration had a good effect on detecting the water abundance in overlying goaf of coal seam at close range, which has guiding significance for water exploration and discharge in goaf.