The influence of five kinds of laboratory synthetic acidification steering main agent 1# to 5# on the viscosity of hydrochloric acid solution was evaluated. The results show that the 5# acidification steering agent not only has better temporary plugging effect, but also breaks acid gel thoroughly and returneds and discharges easily, thus greatly reducing the residual amount of steering agent in the reservoir and the damage to the reservoir. The solubility in acid and the viscosity of the main agent in four kinds of solvents, water, butylcellosolve, ethanol and xylene, were evaluated. The results show that 5# steering agent is easy to dissolve in organic solvent and not in water. The acidification steering agent 5#-2 and 5#-3 are dissolved rapidly in hydrochloric acid, the solution is homogeneous and transparent after 120 min, no precipitation and stratification. The increasing trend of the viscosity of 5#-2 acidification steering agent is slower than that of 5# acidifying agent, and its maximum viscosity is also decreased, and its stable length at the top of the viscosity is longer and it breaks gel quickly. Therefore, butylcellosolve is chosen for the solvent of 5# steering agent. The research show that the effect is the best with 5# the acidification steering agent as main agent, and with butylcellosolve as the solvent of acidification steering agent 5#-2.