The waste emulsion was treated using demulsification and Fenton oxidation, and its influencing factors were studied systematically. The experimental results show when the dosage of calcium chloride was 5 g / L, the stirring time was 30 minutes, the dosage of PAC was 4 g / L, the dosage of APAM was 10 mg / L, the removal rate of COD was 67.38%. After demulsification and precipitation, Fenton oxidation was carried out under acidic conditions. The dosage of ferrous sulfate heptahydrate was 11.12 g / L, 30% hydrogen peroxide was 100 mL/L, and after three hours of reaction, calcium oxide and APAM were added for flocculation and sedimentation, the dosage of calcium oxide was 6.33 g / L, the dosage of APAM was10 mg / L, the COD was reduced to 1 731 mg / L, the removal rate of COD was 92.47%, BOD was decreased to 1 595 mg / L, B / C was 0.92, and the effiluent could enter the biochemical system directly.