Mining causes water pollution, to understand the mining area water pollution situation, applying the matter-element analysis to Fuxin Haizhou open-pit mining area groundwater quality evaluation, according to the mining area groundwater quality status, total hardness, SO42-, CL-, total soluble solids, nitrate pollution factors of representative evaluation are elected. As an understanding of the mining area water quality, the comparison of three away from mine point, seven monitoring points within the mining area. The results showed that the water quality of three control point for Ⅰ-Ⅱ class, water quality is better; Fuxin haizhou open-pit coal mine mining area groundwater quality for Ⅳ-Ⅴ class, water pollution is serious; Matter-element analysis method of the ratio of different evaluation factors were weighted comprehensive evaluation, the evaluation results with systematic, accurate, comprehensive advantages are consistent with RBF neural network evaluation results of the groundwater, illustrating the matter-element analysis method applied well in the assessment of groundwater quality in mining area.