The occurrence environment of deep coal resources was complex, and the prevention and control of water disaster was still a key issue restricting the safe mining of deep coal mines. This paper focused on the geological conditions of the underlying multi-thin limestone and the thick Cambrian limestone in Pingmei No.10 Mine, the water prevention and control characteristics of mining under pressure and the occurrence of water outburst in the upper layer, used the microseism real-time monitoring data to describe its distribution law, and deeply analyzed the characteristics of deep repeated mining pressure behavior. The main results were as follows : The vertical distribution of microseism events showed a significant law of 'near coal seam aggregation'. The rupture height of roof events was negatively correlated with the frequency of microseism events. The amount of events in the middle section of limestone and its depth decreased step by step with the increase of depth. The distribution area was closely related to the position of deep water conducting channel in the working face. In the process of repeated mining, there was a linkage between roof weighting and floor failure. The sudden increase of floor disturbance depth ( increase > 5 m ) occurred within 3 days before all weighting days, indicating that the advanced failure of floor could be used as a pre-warning signal for weighting. With the evolution of the spatial relationship between the mining position and the deep water conducting channel, the microseism events in the middle and deep areas of the floor limestone showed a periodic change of 'from nothing to something, from more to less and then back up'. The research reflected the asymmetry law of shallow water outburst point dispersion and deep water channel concentration, revealed the time and space law of energy release and stress evolution of surrounding rock under repeated mining, and provided quantitative basis for roof control during weighting in deep mines. It also provided theoretical support for accurate forewarning and prevention of floor water disaster.