Aiming at the problem of water disaster prevention and control in confined aquifer of deep coal seam mining, based on the geological and hydrogeological conditions of Jiulong Mine, the mechanism of water outburst disaster in high confined aquifer of coal seam floor was comprehensively analyzed, and the full-cycle three-dimensional control technology was summarized according to the characteristics of water outburst such as high water pressure in deep coal seam, etc. The results showed that for the deep mining face with structure, the pre-mining three-dimensional drainage regional control, the safety monitoring and key reinforcement of the weak area during mining, and the post-mining reinforcement grouting, which improved the safety of mining, and realized water-reducing mining and harmless mining above deep high confined aquifer. The study had reference significance for coal seam mining under similar conditions.