|
|
|
| Analytical Methods of Veterinary Drug Residues in Animal Derived Food |
| HAO Qiu-juan1, MA Tong-suo1, HAO Dong-xu2, LI Jing1, ZHAO Shi-hao1 |
| 1.College of Biological Science and Engineering, Hebei University of Economics and Business, Shijiazhuang 050061, China; 2. Hebei Economics and Management School, Shijiazhuang 050071, China |
|
|
|
|
Abstract Recently, the problem of veterinary drug residues in animal derived food has drawn wide attention in the world. It is imperative to develop rapid, simple, highly sensitive, and high-throughput analytical methods for veterinary drug residues.The development and application of physical and chemical analysis, immune and biosensor detection technology of veterinary drug residues were introduced. Possible future directions in the analytical methods used for veterinary drug residues were also outlined. It is put forward that the development directions of veterinary drug residue analysis testing technology are higher sensitivity and lower detection limit, higher selectivity and specificity and anti-interference ability, analyze more samples per unit time, determine the remains of a variety of veterinary medicine at the same time,realize the integration of pretreatment and determination, develop more combination technologies; reduce pollution and realize the environment friendly, and the screening of veterinary drug residue, and quantitative and corroborate should be further developed and researched.
|
|
|
|
|
|
| [ 1 ] Huan Yu , Yanfei Tao , Dongmei Chen, et al. Simultaneous determination of fluoroquinolones in foods of animal origin by a high performance liquid chromatography and a liquid chromatography tandem mass spectrometry with accelerated solvent extraction[ J ]. Journal of Chromatography B，2012（885-886 ）：150-159.
[ 2 ] Sokol J，Popelka P，Nagy J. Dertermination of tylosin in food of animal origin by liquid chromatography [ J ]. Folia Veterinaria，2010，54（3 ）：167-171.
[ 3 ] 邹 芸. 动物源性食品中胺苯醇类兽药残留检测方法研究[ D ].重庆：西南大学，2009：15-38.
[ 4 ] Gude T，Preiss A，Rubach K. Determination of chloramphenicol in muscle，liver，kidney and urine of pigs by means of immunoaffinity chromatography and gas chromatography with electron- capture detection [ J ]. J Chromatogr B，1995（673 ）：197-204.
[ 5 ] 张祖玲，李建军，屈凌波，等. 毛细管电泳-电致化学发光法测定甲磺酸帕珠沙星[ J ]. 分析化学，2008，36（7 ）：941-946.
[ 6 ] 邵 黎. 鸡肉中恩诺沙星的MISPE-HPCE检测方法的研究[ D ].合肥：安徽农业大学，2009：21-40.
[ 7 ] Choma I，Grenda D，Malinowska I，et al. Determination of umequine and doxycycline in milk by a simple thin-layer chromatographic method [ J ]. J Chromatogr B，1999（734 ）：7-14.
[ 8 ] Xie HZ, Dong C，Fen YL，et al. Determination of doxycycline, tetracycline and oxytetracycline simultaneously by TLC-fluoresence scanning densitometry [ J ].Anal Lett, 1997（30 ）：79-90.
[ 9 ] Gaugain M, Abjean JP. High-performance in-layerchromatographic method for the fluorescence detection of threenitroimidazole residues in pork and poultry tissue [ J ]. J Chromatogr A，1996，737：343 346.
[ 10 ] 陈振桂. 水产品中磺胺类和氯霉素类兽药残留分析方法研究[ D ]. 南昌：南昌大学，2007：21-56.
[ 11 ] 汪纪仓，马素英，王大菊，等. 气相色谱一离子阱串联质谱 法同时测定猪肌肉中硝基咪唑类药物残留量[ J ]. 畜牧兽学报，2008，39（12 ）：1 772—1 778.
[ 12 ] 潘新明，潘守奇，于金玲，等. 液相色谱串联质谱检测动物源性食品中莫西丁克残留[ J ]. 安徽农业科学，2011，39（22 ）：13 563-13 564.
[ 13 ] 郑 晶，黄晓蓉，林 杰，等．应用放射性免疫分析方法快速筛检烤鳗中四环素族药物残留[ J ]．福建水产, 2005,（3 ）：47-49．
[ 14 ] Smith D S，Eremin S A．Fluorescence polarization immunoassays and related methods for simple，high-throughput screening of small molecules．[ J ]．Anal Bioanal Chem，2008,（10 ）：1-9.
[ 15 ] 宋 佩. 免疫分析法在食品有害残留的检测和新药筛选中的应用研究[ D ]. 天津：南开大学，2012：11-42.
[ 16 ] 李岩松.环丙沙星单克隆抗体制备及其在ELISA中的应用[ D ].长春：吉林大学，2005：30-69.
[ 17 ] DUAN J H，YUAN Z H．Development of a11 indirect competitive ELISA for ciprofloxacin residues in food animal edible tissues [ J ].A gric Food Chem，2001，49（3 ）：1 696-1 700.
[ 18 ] 刘 垣，郑文杰，贺 艳，等．胶体金免疫层析法快速检测组织样品中喹诺酮类药物残留[ J ].食品研究与开发, 2009, 30（5 ）：131-135.
[ 19 ] 黄 薇. 磁性免疫层析技术在氯霉素残留快速检测中的应用研究[ D ]. 武汉：华中科技大学，2012：24-43.
[ 20 ] 王西丽，陈巧燕，李金峰，等.C18-磁性纳米颗粒萃取虾肉中氯霉素残留[ J ]. 中国兽药杂志，2012，46（10 ）：20-23.
[ 21 ] 刘国艳，柴春彦．生物传感器技术及其在检测动物性产品中药物残留的应用前景[ J ]．中国兽医学报，2004，11（24 ）：625-627.
[ 22 ] STERNESJO A, MELLGREN C, BJORCK L. Determination of sulfamethazine residues in milk by a surface plasmon resonance-based biosensor assay[ J ]. Analytical Biochemistry, 1995, 226（1 ）：175-181.
[ 23 ] 李 辉，崔大付，王于杰, 等.利用表面等离子谐振生物传感器检测磺胺二甲嘧啶的方法研究[ J ].食品科学，2007，28（6 ）：288-292 |
|
|
|
