Karst collapse column was product of Karst dynamic geologic process, and was geological phenomenon which was extensively developed in north China coalfields. There were too many superlarge water-inrush disasters caused by Karst collapse column in north China. The detection of Karst collapse column needed to be further studied so far. This paper adopted ray tracing theory and the seismic numerical modeling method to study the seismic numerical modeling of Karst collapse columns. The paper took the Karst collapse column in Huainan for example to discuss the seismic numerical modeling of Karst collapse column in level strata and tilt strata. This paper used GXⅡ simulation software and adopted the numerical modeling method of zero offset to verify the seismic response of tapered Karst collapse column under the condition of zero offset and simulated the seismic of ideal condition. The research of this paper on the Karst collapse columns in the detection and simulation had certain theory and application value for mines under the similar conditions.