Initial geostress field was important basis of coal mining engineering design and safety analysis, usually the measured in-situ stress point was little, based on the limited ground stress data, inverse analysis method obtained to get the whole stress field was adopted. Based on the measured data of in-situ stress, combined with Xin’an Mine landform condition and geological structure features, Xin’an Mine ground stress field distribution characteristics were studied; On this basis, finite difference mathematical model of multivariate regression method was adopted, the sixth and seventh mining area of Xin’an Mine three dimensional stress field inversion analysis was conducted, the in-situ stress distribution rule and influence factors were obtained. The result showed Xin’an Mine ground stress field distribution was affected by tectonic stress and geological structure, fold and fault structure factors affected significantly.