The transmittance of ethylene glycol is an important index for evaluating the quality of ethylene glycol and an important basis for the downstream polyester enterprises to measure the reference use of ethylene glycol. In view of the phenomenon that the transmittance of coal-to-ethylene glycol enterprises decreases after a long period of operation, the factors affecting the transmittance of ethylene glycol, such as temperature, vacuum degree, feed load, by-product extraction and opportunity scrubber were discussed. In order to further control the transmittance of distillation, the distillation component. Temperature and vacuum degree of the separation system should be mainly controlled in production.