With the petrochemical, pharmaceutical and other refractory organic wastewater as the research objects, the reactor was arranged with the operation of the device, and the combined process was discussed， the impact resistance ability of the refractory organics was studied. Through the two stage catalytic oxidation and  biological aerated filter combination technology advanced treatment, the refractory organic wastewater which has reached level 1 A (GB18918—2002) emission standards could be recused as reclaimed water.