Amino acetic acid wastewater has the features of big volume, complex composition, long flow of treatment process, high energy consumption and serious environmental pollution etc. that seriously effect the social environment and industry development, advanced treatment of amino acetic acid wastewater become an urgent problem for the enterprises. Centrifugal spray methods was adopted to treat amino acetic acid wastewater in depth. The experimental results show that in the process of using high-speed centrifugal spray dryer, by adding humic acid and other packings, the organic matter in wastewater can be adsorbed effectively, the liquidity of powder can be improved and the content of organic matter in the product can be also improved. The product can be used as organic fertilizer for sale, and be also used as filling material in compound fertilizer factory. This method to treat amino acetic acid wastewater is simple and  feasible, solves the problem plaguing enterprises for many years.