The importance of laboratory management in quality control activities and the commonly used method was introduced, implementation problems should be paid attention to in the laboratory quality control activities were concluded, required combined working type and volume were pointed out, suitable for the actual status of the laboratory quality control plan was established, quality control procedure was settled, and finished in time, concluded at regular intervals, ensured test results were accurate and effective by laboratory, which provided a reference for laboratory management personnel in the practical work of the implementation of quality control activities.