Fangezhuang Mine was taken as example, the hidden disaster of the mine was analyzed and studied by collecting and exploring the geological data in mining, finally, the hidden disaster was settled as collapse column, fault, fracture, gas, goaf, spontaneous combustion of coal seam, poor sealing borehole and water flowing fractured zone, which are threat to safe mining. Based on these factors, the countermeasures were set up, the comprehensive safe technology was adopted in mining, which eliminated hidden danger of accident, prevented disaster and ensured safe mining.