In order to choose the efficient and long-term pesticide to prevent cnaphalocrocismedinalis of paddy rice,the pesticide mixtures poisoning of 5.7% emamectin benzoate and 8% lufenuron and the pesticide mixtures poisoning of 1.8% abamectin were chosed to do field efficacy experiments. The results showed that the pesticide mixtures poisoning of 5.7% emamectin benzoate and 8% lufenuron had the best effect and the death rate was reached 67.7% in the third day. The death rates were 82% and 92.2% respectively in the 5th day and the 7th day. The pesticide mixtures poisoning of 1.8% abamectin had a certain control effect on cnaphalocrocismedinalis and the death rate was 60% in the7th day,but the prevention was no significant with cnaphalocrocismedinalis.