In order to ensure safe actual mining of the deep Shanqing mining face under pressure, this paper analyzes the hydrogeological condition of 56805 mining face in Niuerzhuang Mine with the findings that Daqing limestone aquifer and Ordovician limestone karst aquifer are aquifers that mainly affect coal seam mining. Under natural condition, there is no hydraulic connection between the two. In the mining environment, coal seam bottom water-blocking ability analysis reveals that water-resisting ability of water-resisting layers have not changed much and very similar to natural state. In the end, the water inrush coefficient method is applied to the evaluation on the safety of 56805 working face, the results show that the working face meet the requirements of safety in mining.